Rosanna Sutherby, PharmD

Dr. Rosanna Sutherby is a freelance medical writer and community pharmacist. She received her PharmD degree from Nova Southeastern University College of Pharmacy in Ft. Lauderdale, FL in 2001. She has been residing and practicing pharmacy in North Carolina since then.

Dr. Sutherby’s pharmacy practice has included patient education and medication management for various disease states, including diabetes, cardiovascular disease, mental illness, asthma and pulmonary disease, and pain management. She is a certified immunizer and has worked with a pioneer team of COVID-19 vaccinators in North Carolina.

Dr. Sutherby’s published work spans a variety of topics, including cardiovascular health, sleep disorders, mental health, alcohol and opioid use disorders, vaccine education, and medication use and safety.

Stopping or Changing Biologics in Severe Asthma Leads to Worse Clinical Outcomes

Stopping or Changing Biologics in Severe Asthma Leads to Worse Clinical Outcomes Findings from research presented at the American College of Chest Physicians suggest the importance of selecting the right biologic from the start. For many with severe asthma, biologic therapy has changed the way they live with asthma. Biologics have been shown to reduce the frequency of asthma exacerbations, hospitalizations, emergency room visits, and the need for oral corticosteroids in individuals who once ha

Mindfulness-Based Stress Reduction Improves Asthma Control and Reduces Airway Inflammation

Studies have shown that individuals with asthma as well as mood or anxiety disorders and psychological distress tend to have poorer control of their asthma, more severe symptoms, and greater utilization of healthcare services than asthma patients without these conditions. Additionally, chronic stress aggravates asthma symptoms and promotes type 2 inflammatory responses, such as those seen in severe asthma. Mindfulness-based stress reduction (MBSR) is a nonpharmacological approach for treating c

Removing the CD47 ‘Do Not Eat Me’ Sign

Macrophages, which are cells that engulf or “eat” other cells, are key players in the body’s immune response. But they need some guidance. Checkpoints built into human cells keep macrophages and the immune response from going amiss. A protein called cluster of differentiation 47 (CD47) is a main checkpoint for macrophages. The presence of this marker on a cell acts as a “do not eat me” sign for macrophages. CD47 is ubiquitous in healthy cells and overexpressed in many myeloid malignancies, incl

Drugs on the Fast Track as Treatments for PTSD

Post-traumatic stress disorder (PTSD) is a chronic psychiatric condition that occurs in some people after experiencing or witnessing traumatic events, such as military combat trauma, childhood trauma and physical or sexual assault. PTSD is associated with several uncontrolled and debilitating symptoms typically triggered by trauma reminders, including nightmares, intrusive thoughts, flashbacks, hypervigilant behaviors, avoidance of traumatic reminders and sleep disruptions. People with PTSD are

Asthma Exacerbations Associated With Poor Lung Function

Exacerbations are believed to be a significant but potentially modifiable cause of declining lung function in some people.Loss of lung function over time is associated with comorbidities, including chronic shortness of breath and premature death. Asthma exacerbations can wreak havoc in patients’ lives. Difficulty breathing can result in frequent trips to the emergency room visits, absences from work and a host of other problems. Asthma exacerbations are also associated with healthcare costs, bu

Treatment for Hemophilia: Many Decisions, Some Difficult, All Should Be Shared

Treatment for Hemophilia: Many Decisions, Some Difficult, All Should Be Shared The hemophilia organization developed a shared decision-making tool for patients and providers. With the anticipated regulatory approval of novel hemophilia gene therapies, many in the hemophilia community have identified the need for and importance of people with hemophilia to fully participate in a shared decision-making process with healthcare professionals. In a paper published last June in the journal Patient P

Judging Up-and-Coming Hemophilia Treatments

Long-acting recombinant replacement factor gets favorable rating from multidisciplinary group. Gene therapy was viewed with some wariness. Anticipated agency approvals of emerging innovative hemophilia treatments are bound to disrupt healthcare organizations and patient care management. The pipeline includes subcutaneously administered coagulation factor replacements, treatments with a longer duration of action and potentially curative gene therapy. In a pilot study published in PLOS ONEin Sept

Asthma Education Program in a Hispanic Community Proves To Be Cost Effective

Asthma Education Program in a Hispanic Community Proves To Be Cost Effective Program in Hidalgo, Texas, cost less than $250 per family. A study found that the intervention saved each household an average of $36 per day. According to the U.S. Department of Health and Human Services, Hispanic people with asthma are twice as likely to have emergency room visits due to asthma-related events compared with non-Hispanic white individuals. Additionally, Hispanic children are 40% more likely to die fro

Predicting Loss of Lung Function in Children With Asthma

Children with nonsevere and severe asthma are more likely to have declining lung function throughout childhood and into adulthood. Yet predictors of which children will experience poor lung function in have not been thoroughly explored or identified In a study published in August 2022 in the Journal of Allergy and Clinical Immunology, researchers used data from the Severe Asthma Research Program (SARP) 3 pediatric cohort study to discover phenotypic factors that contribute to declining lung fun

Diabetes and HIV May Increase Risk of Hypertension in People with Hemophilia

Diabetes and HIV May Increase Risk of Hypertension in People with Hemophilia Findings suggest that screening people with hemophilia for diabetes and hypertension might have benefits. A study published in the journal Haemophilia in July 2022 found that diabetes and human immunodeficiency virus (HIV) infection increase the risk of hypertension in men with hemophilia. This is of concern in the hemophilia population because both diabetes and hypertension are associated with an increased risk of in

Gene Therapy for Severe Hemophilia B Could Be More Cost Effective Than Current Treatments

Gene Therapy for Severe Hemophilia B Could Be More Cost Effective Than Current Treatments An analysis found that a single dose of gene therapy would be more cost-effective than on-demand or prophylaxis factor replacement in 92% of cases. Hemophilia is a hereditary, lifelong, and life-threatening disorder that, until recently, has had no prospective cure. Gene therapy might change that, but the cost has been predicted to be in the millions. Individuals with hemophilia have a gene mutation that

An NIH Trial of Severe Asthma Treatment Tailored to Subtypes

An NIH Trial of Severe Asthma Treatment Tailored to Subtypes Repurposing Gleevec as an asthma drug is one of the possibilities that the PrecISE trial of severe asthma is examining. The trial has an adaptive design. Although severe asthma accounts for only 3% to 10% of the adult population with asthma, it makes up more than half of healthcare expenses related to asthma. Some of that cost includes the development of new and effective treatments. People with severe asthma have difficult-to-contro

A Possible Link Between Acid Reducers and Asthma

Acid suppressants, particularly proton pump inhibitors (PPIs) and histamine-2 receptor antagonists (H2 blockers), are often prescribed to treat gastroesophageal reflux and gastroesophageal reflux disease (GERD) in infants. The PPIs include drugs such as lansoprazole, which is sold under the brand name Prevacid, and omeprazole, sold under the brand name Prilosec. The H2 blockers include cimetidine, sold as Tagamet, and famotidine, sold as Pepcid AC. Evidence of the efficacy of the acid blockers i

Gene Therapies for Hemophilia. Possibly Curative, Likely Ultraexpensive

Hemophilia is a rare, X-linked, hereditary bleeding disorder characterized by blood clotting factor deficiencies that affects mainly males. It results in excessive bleeding, particularly in the joints, soft tissues and muscles. The bleeding usually happens after internal or external trauma, but in rare cases, it occurs spontaneously. According to the CDC, up to 33,000 males in the United States live with hemophilia, but the condition can be fatal. Hemophilia is divided into subtypes, the two mos

Contrave and Price: Reducing Long-Term Drugs Costs and More

If you’re looking at options for weight management, you may want to learn more about Contrave. Contrave is a prescription drug that’s used with a balanced diet and exercise to help manage weight in adults who: • are overweight and have at least one weight-related condition, such as type 2 diabetes, high blood pressure, or high cholesterol Contrave has two active ingredients: naltrexone and bupropion. (An active ingredient is what makes a drug work.) This medication comes as an extended-release t

Cosentyx and Price: Reducing Long-Term Drug Costs and More

If you’re looking at treatment options for certain inflammatory conditions, you may want to learn more about Cosentyx (secukinumab). It’s a prescription drug that’s used to treat the following conditions in adults and some children: • arthritis related to enthesitis (inflammation in the areas of your bones where tendons and ligaments attach) Cosentyx is also used to treat the following conditions in adults: • inflammatory spondylarthritis that doesn’t show up on X-rays The active ingredient in C

Repatha Side Effects: What They Are and How to Manage Them

If you have certain heart conditions, your doctor might suggest Repatha as a treatment option. It’s a prescription drug used to: • lower levels of certain kinds of cholesterol in adults and some children with specific conditions • reduce the risk of heart attack or stroke, or the need for certain heart surgeries in adults with heart disease If you and your doctor agree that Repatha is safe and effective for you, you’ll likely use it long term. The active ingredient in Repatha is evolocumab. (An

Pentasa Side Effects: What They Are and How to Manage Them

If you have ulcerative colitis (UC), your doctor might suggest Pentasa as a treatment option for you. It’s a prescription drug used to do the following in adults: Pentasa comes as an extended-release capsule that you swallow. It contains the active ingredient mesalamine. (An active ingredient is what makes a drug work.) If you and your doctor decide it’s safe and effective for you, you’ll likely take Pentasa long term. For more information about Pentasa, including details about its uses, see thi

Rapamune Side Effects and How to Manage Them

If you have a certain lung condition or are receiving a certain kind of organ transplant, your doctor might suggest that you take Rapamune. Rapamune is a prescription drug used for: • preventing kidney transplant rejection in adults and some children The active ingredient in Rapamune is sirolimus. An active ingredient is what makes a drug work. Rapamune comes in two forms: For more information about Rapamune, including details about its uses, see this in-depth article. Like other drugs, Rapamune

Anxiety, Depression, and Diabetes Higher in Older Males with Hemophilia; Cardiovascular Disease Lower

Anxiety, Depression, and Diabetes Higher in Older Males with Hemophilia; Cardiovascular Disease Lower Lack of blood clotting may afford some protection against common cardiovascular disease events, such as ischemic stroke. People living with hemophilia now can expect a longer lifespan than those who had the disease decades ago. Thanks to new advances in treatment, people with hemophilia now have an average life expectancy close to that of people without hemophilia. However, living into older a
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